Each cruise line will be different and I would do lots of research. John is still very high functioning and can handle many situations so we take a "cheap" cruise on Carnival which is geared towards families. The other lines have more amenities and just need to be contacted to ask what they have. Each line will assign you a personal representative who will answer your questions about the where's, what's, and why's. I imagine that you will find Royal Caribbean, Norwegian, the smaller cruise ships on the east coast in the northern states and on the rivers, in the US, etc. more accommodating. It will entirely depend upon each line and exactly what your needs are for your loved one. We loved the Holland America when we went to Alaska because it was full of older adults and was not the "party boat" that we saw with Carnival. But both had great food and similar cabins. The Holland American had a higher quality of entertainment especially in music. Food was wonderful in both. In all the ships there are so many wonderful places to sit and just watch the world go by. They are outside, inside, eating, walking and all contained. Bit of trivia--anyone over the age of 70 will probably not be given seasick patches so be prepared with Dramamine or other products recommended by the doctor. Also, take out the additional insurance coverage if you leave the States as Medicare will not follow you.